Читать книгу Clinical Reasoning in Veterinary Practice - Группа авторов - Страница 53

The CRTZ is located in the area postrema in the floor of the 4th ventricle. It has no BBB, therefore allowing toxins and chemicals that would normally be excluded from the CNS access to the brain. The CRTZ is stimulated by endogenous toxic substances produced in acute infectious diseases or metabolic disorders such as uraemia or diabetic ketoacidosis as well as by drugs and exogenous toxins.