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1.6.1 Definition of Efflux and Influx Transporters

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Drug transporters can be categorized as efflux or influx transporters according to the direction they transport substrate across the cell membranes. This classification is often observed in the literature where drug transport studies are performed at the cellular level. With this definition, transporters that pump the substrates out of the cells are called efflux transporters, whereas transporters that transfer substrates into cells are called influx transporters.

Drug Transporters

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