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Cytology

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The use of cytological techniques in the diagnosis of vulval disorders is limited, with conflicting results reported in studies. Poor correlation of vulval Pap smear cytology with subsequent histological analysis of neoplasia has been reported [8], but the specificity and sensitivity may be increased with the use of a scalpel technique [9]. Vulval brush cytology may be useful as a triage technique for deciding which patients may require a biopsy for clinically suspicious lesions [10]. Histological examination of a tissue sample should always be regarded as the gold standard.

However, for a rapid diagnosis of herpes simplex infection, a Tzanck smear is helpful.

Ridley's The Vulva

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