Читать книгу Ridley's The Vulva - Группа авторов - Страница 169

If a Type 1 allergic reaction is suspected, this is most likely to be due to either semen or latex in the context of vulval symptoms. Prick testing may be required if this type of allergy is suspected, and the patient should be referred to an allergy clinic, where full facilities for resuscitation are available. It detects allergen specific IgE bound to mast cells which degranulate and release histamine, causing a weal at the site of testing. Oral antihistamines should be stopped a few days beforehand.

A small drop of the allergen is placed on the skin, most commonly on the forearm, and then a small prick is made through the liquid with a lancet. A positive control of histamine is used with a negative control of saline. The tests are read after 15–20 minutes, and an urticarial weal of 3 mm or more is regarded as positive.

Patient information about prick testing

https://dermnetnz.org/topics/skin‐prick‐testing/. Last accessed September 2021.