Читать книгу Vertical 2: The Next Level of Hard and Soft Tissue Augmentation - Istvan Urban - Страница 12

The osseoinductive action of BMP-2 depends on the presence of mesenchymal cells. The question is: How important are these types of cells in the periosteum versus the bone surface and the blood clot?

Dense versus perforated membrane was compared in a chronic vertical defect (Figs 1-22 to 1-24). The results demonstrated significantly more bone fill when using the perforated membrane. The non-perforated membrane usually demonstrated appositional bone formation from the host bone with a lack of bone formation under the membrane (Figs 1-25 to 1-27). These results demonstrated that the communication with the periosteum might be important when a graft containing BMP-2 is being used, such as autogenous particles.