Читать книгу Principles of Virology - Jane Flint, S. Jane Flint - Страница 149

The introduction of foreign DNA into cells is called DNA-mediated transformation to distinguish it from the oncogenic transformation of cells caused by tumor viruses and other insults. The term “transfection” (transformation-infection) was coined to describe the production of infectious virus after transformation of cells by viral DNA, first demonstrated with bacteriophage lambda. Unfortunately, the term “transfection” is now routinely used to describe the introduction of any DNA or RNA into cells. In this textbook, we use the correct nomenclature: the term “transfection” is restricted to the introduction of viral DNA or RNA into cells with the goal of obtaining virus reproduction.