Читать книгу Principles of Virology - Jane Flint, S. Jane Flint - Страница 191

The foundation of the envelopes of all animal viruses is a lipid membrane acquired from the host cell during assembly. The lipid composition is variable, because viral envelopes can be derived from different kinds of cellular membranes. Embedded in the membrane are viral proteins, the great majority of which are glycoproteins that carry covalently linked sugar chains, or oligosaccharides. Sugars are almost always added to the proteins posttranslationally, during transport to the cellular membrane at which progeny virus particles assemble. Intra- or interchain disulfide bonds, another common chemical feature of these proteins, are also acquired during transport to assembly sites. These covalent bonds stabilize the tertiary or quaternary structures of viral glycoproteins.