Читать книгу Principles of Virology - Jane Flint, S. Jane Flint - Страница 68

Replication of viral genomes requires the cell’s synthetic machinery in addition to viral proteins (see Chapters 6, 7, and 9). The cell provides nucleotide substrates, energy, enzymes, and other proteins. Transport systems are required because the cell is compartmentalized: essential components might be found only in the nucleus, the cytoplasm, or within subcellular organelles. Study of the mechanisms of viral genome replication has established fundamental principles of cell biology and nucleic acid synthesis.