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Оглавление

Hypoglycemia

BASICS

DEFINITION/OVERVIEW

Abnormally low blood glucose concentration. In most species, glucose concentrations fluctuate; normal concentrations range from 60 mg/dl to 200 mg/dl (3.3–11 mmol/l), but lower values could be normal.

ETIOLOGY/PATHOPHYSIOLOGY

 Exhaustion, starvation, malnutrition

 Septicemia

 Hepatobiliary disease

 Pancreatic disease

SIGNALMENT/HISTORY

 Animals with severe systemic disease may be predisposed.

 Long‐lasting anorexia

CLINICAL PRESENTATION

 Weakness

 Tremors

 Loss of righting reflex

 Torpor

 Unresponsiveness

RISK FACTORS

Husbandry

Poor nutritional status

Others

Systemic disease

DIAGNOSIS

Blood glucose levels below 20 mg/dl (1.1 mmol/l) indicate hypoglycemia.

DIFFERENTIAL DIAGNOSIS

N/A

DIAGNOSTICS

 Detection of hypoglycemia in a clinically healthy animal should not cause concern.

 In animals with clinical signs and hypoglycemia, attempts should be made to rule out septicemia, hepatobiliary disease, and pancreatic neoplasia.

 Glucose may be artificially low in blood samples stored for a prolonged period prior to separation of plasma/serum.

PATHOLOGICAL FINDINGS

 Depends on underlying etiology

 • The pancreas should be thoroughly evaluated.

TREATMENT

APPROPRIATE HEALTH CARE

N/A

NUTRITIONAL SUPPORT

Consider energy‐rich nutritional support by stomach tube in cases of anorexia.

CLIENT EDUCATION/HUSBANDRY RECOMMENDATIONS

If related to poor nutrition and management, educate clients on appropriate feeding practices.

MEDICATIONS

DRUG(S) OF CHOICE

 Treat underlying disease

 Supportive administration of glucose or dextrose parenterally (e.g., 2.5% in 0.45% saline, 20–40 mL/kg SC) or orally (3 g/kg PO) may be indicated.

PRECAUTIONS/INTERACTIONS

N/A

FOLLOW‐UP

PATIENT MONITORING

Monitor glucose levels and clinical signs.

EXPECTED COURSE AND PROGNOSIS

 If related to nutritional status prognosis is good.

 If secondary to severe systemic disease prognosis is poor.

MISCELLANEOUS

COMMENTS

N/A

ZOONOTIC POTENTIAL

N/A

SYNONYMS

N/A

ABBREVIATIONS

PO = per os

SC = subcutaneous

INTERNET RESOURCES

Kaplan M. Hypoglycemia and Hyperglycemia in Reptiles. Melissa Kaplan’s Herp Care Collection, January 1, 2014. www.anapsid.org/diabetes.html .

Suggested Reading

1 Campbell TW. Clinical pathology. In: Mader DR, Divers SJ, eds. Current Therapy in Reptile Medicine and Surgery. St. Louis, MO: Elsevier; 2014:70–92.

2 Stahl SJ. Hyperglycemia in reptiles. In: Mader DR, ed. Reptile Medicine and Surgery. 2nd ed. St. Louis, MO: Elsevier Saunders; 2006:822–830.

Author Mads F. Bertelsen, DVM, DVSc, DACZM, DECZM (Zoo Health Management)

Blackwell's Five-Minute Veterinary Consult: Reptile and Amphibian

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