Читать книгу Understanding Anatomy and Physiology in Nursing - John Knight - Страница 130

This hormone is produced by the atria of the heart in response to increased blood volume. If blood volume increases, the atria are subjected to increased stretch, with the atrial myocytes (muscle cells) releasing ANP at concentrations proportional to the degree of stretch. ANP is a powerful natural diuretic peptide and stimulates the kidneys to produce a large amount of dilute urine to normalise the total blood volume. ANP and ADH can be seen to be antagonistic to each other in terms of regulating blood volume and blood pressure. The physiology of these hormones and their effects on the kidney are discussed in greater detail in Chapter 11.