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Case study: Josie revisited – breast cancer evidence-based practice

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Josie was fortunate to detect the lump in her breast while the tumour mass was small and quickly underwent surgery (lumpectomy) to remove the cancerous tissue. Following histological examination it was determined that the malignant cells forming Josie’s tumour expressed the human epidermal growth factor receptor 2 (HER2). Drugs that block this receptor such as Herceptin have recently become available, which provide a new tool for treating breast cancer.

Herceptin can slow the growth of breast tumour cells and when used in early breast cancer can reduce the risk of recurrence. Josie was relieved to be told by her consultant that since her tumour mass was small, chemotherapy would not be required and since beginning her Herceptin treatment six months ago tests have revealed that Josie is currently free of the disease.

Targeted drugs such as Herceptin are revolutionising the treatment of many forms of cancer, with new targeted therapies continually being developed and made available.

Now that you have completed the chapter, attempt the multiple-choice questions in Activity 1.5 to assess your knowledge.

Understanding Anatomy and Physiology in Nursing

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