Читать книгу Population Genetics - Matthew B. Hamilton - Страница 27
Problem box 2.1 The expected genotype frequency for a DNA profile
ОглавлениеCalculate the expected genotype frequency and odds ratio for the 10‐locus DNA profile below. Allele frequencies are given in Table 2.3.
D3S1358 | 17, 18 |
vWA | 17, 17 |
FGA | 24, 25 |
Amelogenin | X, Y |
D8S1179 | 13, 14 |
D21S11 | 29, 30 |
D18S51 | 18, 18 |
D5S818 | 12, 13 |
D13S317 | 9, 12 |
D7S820 | 11, 12 |
What does the amelogenin locus tell us and how did you assign an expected frequency to the observed genotype? Is it likely that two unrelated individuals would share this 10‐locus genotype by chance? For this genotype, would a match between a crime scene sample and a suspect be convincing evidence that the person was present at the crime scene?