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Problem box 2.1 The expected genotype frequency for a DNA profile

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Calculate the expected genotype frequency and odds ratio for the 10‐locus DNA profile below. Allele frequencies are given in Table 2.3.

D3S1358 17, 18
vWA 17, 17
FGA 24, 25
Amelogenin X, Y
D8S1179 13, 14
D21S11 29, 30
D18S51 18, 18
D5S818 12, 13
D13S317 9, 12
D7S820 11, 12

What does the amelogenin locus tell us and how did you assign an expected frequency to the observed genotype? Is it likely that two unrelated individuals would share this 10‐locus genotype by chance? For this genotype, would a match between a crime scene sample and a suspect be convincing evidence that the person was present at the crime scene?

Population Genetics

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