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3.2.1 Penicillin V Oral Suspension

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Steps to follow when prescribing for a pediatric patient: www.drugguide.com/ddo/ub/view/Davis‐Drug‐Guide/109514/0/Pediatric_Dosage_Calculations

 What is the dose for the age of the child? This information can be obtained from a drug reference source. This is a set dosage for a child of that age and weight.Dose required: <12 year: 15–30 mg/kg/d q6–8 h; max. 3 g/day × 7–10 days (this is an established dosage obtained from a drug reference source).

 If it is decided to give an oral suspension, the amount of active ingredient in the suspension must be known. This information is also obtained from a drug reference book.How supplied: oral suspension 125 mg/5 mL; 250 mg/5 mL (100 mL bottle).Table 3.3 Calculation for correct dose to give to a pediatric patientStep 1 Convert pounds to kg:70 lb × 1 kg/2.2 lb = 31.8 kgStep 2 Calculate the dose in mg:31.8 kg × 15 mg/kg/day = 477 mg/dayStep 3 Divide the dose by the frequency:477 mg/day ÷ 3 (tid) = 159 mg/dose q8hStep 4 Convert the mg dose to mL:159 mg/dose ÷ 125 mg/5 mL = 6.36 mL qidStep 5 Convert mL to teaspoonfulsa6.36 mL ÷ 5 mL = 1.27 teaspoonful (round to 1¼ teaspoonful)a Each teaspoonful is 5 mL.Calculation for 159 mg/dose ÷ 125 mg/5 mL is the following: 159 x 5 ÷ 125 = 6.36.Table 3.4 How the prescription is writtenRx Penicillin V oral suspension 250 mg/5 mLDisp: 1 bottle (100 mL)Sig: Take 1¼ teaspoonful orally three times a day for 7 days for dental infectioAdvise the parent to use a medicine dropper/spoon rather than an ordinary teaspoon because of variations in measurements. After penicillin V solution is mixed, it is best to store it in a refrigerator between 2 °C and 7 °C (36–46 °F); do not freeze. Throw away any unused medicine after 14 days.

 Now, the correct dose to give to the pediatric patient must be calculated (Table 3.3).

 How is the prescription written (Table 3.4)?

The Dentist's Drug and Prescription Guide

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