Читать книгу Welcome to the Genome - Michael Yudell - Страница 2
Table of Contents
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2 FOREWARD: STILL, THE GENOMIC REVOLUTION
4 INTRODUCTION: WELCOME BACK TO THE GENOME REFERENCES
5 1 From Mendel to Molecules IN THE ABBEY GARDEN IN THE FLY ROOM EUGENICS—“PREVAILING SPEEDILY OVER THE LESS SUITABLE” “A VERITABLE ‘AVALANCHE’ OF NUCLEIC‐ACID RESEARCH” A STRUCTURAL MILESTONE REFERENCES
6 2 The Building Blocks of Gene Sequencing RESEARCH MILESTONE 1: INVENTION OF DNA SEQUENCING TOOLS RESEARCH MILESTONE 2: DECIPHERING THE GENETIC CODE RESEARCH MILESTONE 3: SYNTHESIZING DNA RESEARCH MILESTONE 4: SEEING GENES RESEARCH MILESTONE 5: COPYING DNA RESEARCH MILESTONE 6: SEQUENCING A VIRAL GENOME RESEARCH MILESTONE 7: THE ULTIMATE DNA COPYING TOOL REFERENCES
7 3 Sequencing the Genome FROM GENE TO GENOME THE SEQUENCE RACING TO THE FINISH REFERENCES
8 4 The Next Generation NEXT GENERATION SEQUENCING HOW MANY GENES DO HUMANS REALLY HAVE? REFERENCES
9 5 Making the Genome Safe A SHAMEFUL PAST PREPARING FOR THE GENOME WHAT CAN RESEARCHERS, UNIVERSITIES, AND COMPANIES DO WITH YOUR GENETIC MATERIAL? THE ETHICS OF DTC GENETIC TESTING WHO OWNS YOUR GENES? MONITORING OUR GENOMIC FUTURE PREPARING THE WORLD FOR CRISPR THE BUSINESS OF BIOLOGY NATURE/NURTURE REFERENCES
10 6 The Meanings of Genetic Diversity: Part I A ROGUES’ GALLERY OF COMPLETED HUMAN GENOMES ASSESSING HUMAN VARIATION USING GENOMES NEXT GENERATION SEQUENCING USING TARGETED CAPTURE OUR GENOMIC PLACE IN THE WORLD REFERENCES
11 7 The Meanings of Genetic Diversity: Part II THE HUMAN GENOME PROJECT AND HUMAN GENETIC DIVERSITY THE STRANGE CAREER OF SCIENTIFIC RACISM UNDERMINING THE RACE CONCEPT THE HUMAN GENOME PROJECT AND THE FUTURE OF RACE CONTINUED MISSTEPS OR A PATH TO THE FUTURE? REFERENCES
12 8 The Tree of Life: 4 Billion Years of Divergence INHERITING A CONTROVERSY THE TREE OF LIFE COMPARATIVE GENOMICS BIODIVERSITY AND GENOMICS REFERENCES
13 9 Sequencing the Small and Infamous: A Look at Metagenomics and Microbiomes WHOLE‐GENOME SEQUENCING HELPS IDENTIFY DANGEROUS MUTATIONS MORE THAN ONE GENOME AT A TIME: MICROBIAL ECOLOGY, METAGENOMICS, AND MICROBIOMES OMES EVERYWHERE REFERENCES
14 10 The World to Come: Agriculture GMOs: THE BASICS RECENT CHANGES IN GENE‐BASED TECHNOLOGY FOR GENETIC MODIFICATION SYNTHETIC BIOLOGY A PLATE FULL OF GM FOODS TRENDS IN ECONOMIC USE OF GM FOODS ISSUES AND ETHICS: THE FOOD CHAIN AND UNINTENDED EFFECTS LABELING GM FOODS CHANGING ATTITUDES TOWARD GM FOOD REFERENCES
15 Conclusion: Conclusion: Don’t Believe the Hype (Including Ours) REFERENCES
16 INDEX
