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2.6.2 Secondary Structure

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The term secondary structure describes the geometry of the long‐chain backbone of the individual protein macromolecule. This geometry can consist of randomly coiled chain along with regions composed of a regular repeating pattern. It is strongly influenced by two key factors

 The stereochemistry of the amide bond

 Hydrogen bonding between the oxygen atom of the carbonyl (C=O) group and the hydrogen atom of the amino (N–H) group in the chain backbone.

Materials for Biomedical Engineering

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