Читать книгу Constitutional Oncogenetics - Noureddine Boukhatem - Страница 4

1 IntroductionFigure I.1. Global path of the index patient and their family members in the onc...

2 Chapter 1Figure 1.1. Familial pancreatic cancer in a syndromic context; identification of...Figure 1.2. BRCA2 mutations are associated with breast and ovarian cancer, but a...Figure 1.3. Incomplete penetrance. Individual II3 is an obligatory carrier of th...Figure 1.4. Identifying at-risk individuals in the family (by testing family mem...Figure 1.5. Fanconi disease: autosomal recessive transmission. Both parents are ...

3 Chapter 2Figure 2.1. Autosomal dominant transmission Lynch syndrome (MMR +/–): (a) involv...Figure 2.2. CMMRD syndrome (constitutional MMR deficiency) recessive autosomic t...Figure 2.3. Virtual colonoscopy can create a three-dimensional (3D) anatomical m...Figure 2.4. Bladder cancer. Computed tomography (CT) scan of the bladder showing...

4 Chapter 3Figure 3.1. De novo mutations are more or less frequent according to the genes i...Figure 3.2. Family tree showing index case c2 (black arrow) diagnosed with invas...Figure 3.3. Astrocytomas. For a color version of this figure, see www.iste.co.uk...

5 Chapter 4Figure 4.1. (a) Countless polyps are present throughout the colon and rectum, ra...Figure 4.2. Classification of colorectal cancer predisposition syndromes

6 Chapter 5Figure 5.1. MEN1 pedigree; d.: death; dx: age at diagnosis

7 Chapter 6Figure 6.1. Adrenal pheochromocytoma: (a) computed tomography (CT) scan of an ad...Figure 6.2. History of publications linking methylation defects to cancer

8 Chapter 7Figure 7.1. BHD renal tumors, bilateral. Axial view of the mid-section of an ind...

9 Chapter 9Figure 9.1. Beauty spotsFigure 9.2. MelanomasFigure 9.3. Pancreatic cancer in the context of family aggregationFigure 9.4. Metastatic melanoma: (a) computed tomography (CT) scan of the rib, s...

10 Chapter 10Figure 10.1. Photograph of basal cell carcinoma

11 Chapter 17Figure 17.1. VHL, hemangioblastoma. For a color version of this figure, see www....Figure 17.2. VHL, renal tumors, bilateral. For a color version of this figure, s...

12 Chapter 19Figure 19.1. HLRCC, renal tumor. For a color version of this figure, see www.ist...