Читать книгу Essential Endocrinology and Diabetes - Richard I. G. Holt - Страница 95

 If underactivity suspected: try to stimulate it

 If overactivity suspected: try to suppress it

Dynamic tests can be split into two categories: provocative ones to interrogate suspected inadequate function; or suppression tests, taking advantage of negative feedback to investigate potential overactivity (Box 4.2). For instance, ACTH is injected to see if cortisol secretion rises in suspected adrenocortical inadequacy (Addison disease; Chapter 6); whereas dexamethasone, a potent synthetic glucocorticoid, is given to see if pituitary ACTH and consequently cortisol secretion is appropriately diminished. If it is not, it implies that the adrenal cortex is overactive (Cushing syndrome; Chapter 6).