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Preface

Over 20 years ago, platelet concentrates entered into the medical field as a means to deliver autologous growth factors responsible for favoring wound healing. During this time span, it has gained widespread acceptance in many fields of medicine due to its more natural delivery system.

Most notably, the past 5 years have seen a tremendous increase in publications on PRF, with over 200 scientific peer-reviewed papers being published each and every year. During this span, a marked increase in our understanding of PRF therapy has been made with respect to selection of appropriate centrifugation devices, impact of tube chemistry on clotting, the optimization of protocols to better concentrate PRF, and even the ability to extend the working properties of PRF from 2–3 weeks toward 4–6 months using a simple heating process. Collectively, we continue to gather new knowledge, and as a result, PRF therapy has become one of the fastest-growing therapeutic options in dentistry. Thousands of users have now benefited from this technology, and this number is only expected to continue to increase.

This book is very different from others in its concept design. More than a dozen expert researchers and clinicians alike were gathered as editors across their different fields of expertise. As section editors, these true experts of their respective disciplines were able to produce a much higher overall quality of this textbook. I am grateful for their encouraging team spirit, their effort in bringing this book to an entirely new level, and their level of professionalism and mindset that ultimately led to this comprehensive textbook. I am also grateful to the numerous clinicians who have provided videos to better educate/demonstrate surgical techniques and concepts with PRF, which will greatly enhance the learning experience of the reader.

The book is divided into four primary sections, including (1) biology of PRF, (2) periodontology, (3) implant dentistry, and (4) additional dental and medical applications. The book aims to take the reader from a basic biologic understanding of PRF through explanations of the various protocols utilized followed by application of these concepts in numerous clinical scenarios.

I therefore am thrilled to introduce our textbook titled Understanding Platelet-Rich Fibrin. I hope you enjoy learning the many aspects centered around the use of PRF in regenerative dentistry.

Acknowledgments

To my parents, family, and friends who have all sacrificed far too often in my pursuit of a career in academic dentistry.

To my classmates, colleagues, and mentors who constantly raised the bar and strived for better.

To Quintessence Publishing for your thorough input in the editing, illustrations, and design of this textbook.

To my family at Lakewood Ranch Dental in Florida who have made clinical practice as enjoyable an experience as can be on a daily basis.

To all leaders and researchers alike who have contributed enormously to the field of PRP/PRF and laid the foundation for this textbook to be written.

To the faculty in the Department of Biomedical Sciences and Cell Biology at the University of Western Ontario (London, Canada; BMSc, MSc), the Dental School at the University of Laval (Quebec; DDS), the Department of Music at Berklee College (Boston; MMus), the Department of Periodontology at the University of Bern (PhD, Dr med dent), the Department of Oral Implantology at Wuhan University (China; postdoctoral research fellow), the Plastic Surgery Department at Queen Mary University (London; clinical masters in facial esthetics), and the Department of Periodontology at the University of Illinois at Chicago (clinical masters in periodontology). Your education and mentorship has provided endless opportunities.

And lastly, to the team at Advanced PRF Education (www.prfedu.com) for making excellence in teaching a top priority.