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Rudy Bilous
Handbook of Diabetes
Читать книгу Handbook of Diabetes - Rudy Bilous - Страница 1
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Страница 1
Table of Contents
List of Tables
List of Illustrations
Guide
Pages
Страница 7
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Chapter 3 Diagnosis and classification of diabetes
Intermediate categories of hyperglycaemia: Pre‐diabetes
Classification of diabetes
CASE HISTORY
LANDMARK TRIALS
WEBSITES
FURTHER READING
Chapter 4 Public health aspects of diabetes KEY POINTS
Primary prevention of Type 2 Diabetes
Providing access to structured diabetes education
Improving diabetes treatment and care
Commissioning diabetes services
LANDMARK CLINICAL TRIALS
FURTHER READING
Chapter 5 Normal physiology of insulin secretion and action, and the incretin effect KEY POINTS
Islet structure and function
Insulin synthesis and insulin polypeptide structure
Insulin secretion
The incretin effect
Insulin receptor signalling
The family of GLUT transporters
FURTHER READING
Chapter 6 Epidemiology and aetiology of type 1 diabetes KEY POINTS
Introduction
Epidemiology
Aetiology Autoimmunity
Box 6.1
Autoimmune disorders associated with type 1 diabetes.
Genetics
Environmental and maternal factors
Viruses
Apoptosis
Dietary factors
Toxins
Animal models
Hygiene hypothesis
Accelerator hypothesis
Stages of Diabetes
Prevention Trials
Screening for Type 1 Diabetes
CASE HISTORY
LANDMARK STUDY
KEY WEBSITES
FURTHER READING
Chapter 7 Epidemiology and aetiology of type 2 diabetes KEY POINTS
Prevalence rates and global burden
Urban versus rural
Impaired glucose tolerance
Incidence
Risk factors for type 2 diabetes Obesity
Physical exercise and diet
Insulin resistance
Hormones and cytokines
Inflammation
Genetics
Thrifty phenotype hypothesis
Metabolic syndrome
β cell dysfunction
Conclusion
LANDMARK CLINICAL TRIALS
KEY WEBSITES
FURTHER READING
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