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The tissue damage associated with exposure to HAVS may affect vascular, neurologic, and musculoskeletal structures in the hands, wrist, or forearm. Damage to these various systems may progress at different rates (Pelmear, 2003). The vascular component is also known as VWF and is related to Raynaud’s phenomenon, which is the most recognized manifestation of HAVS. The precise pathological mechanism is not totally clear; however, it is believed that vibration exposure causes endothelial damage through mechanical trauma and oxidative stress, leading to vasoconstriction through activation of the sympathetic nervous system. Nerve fibers (both myelinated and nonmyelinated) are thought to be damaged through vibration exposure. Musculoskeletal symptoms may be due to direct damage to musculoskeletal tissues due to the repetitive forces of vibration and/or may be secondary to nerve damage (Shen & House, 2017).