Читать книгу Anti-Aging Therapeutics Volume XIII - A4M American Academy - Страница 31

Two of the overlooked aspects of increasing dietary B-Sit are: a) it stimulates the sphingomyelin cycle through increased ROS1 activity, which increases cell proliferation as demonstrated in PCa cells; b) high levels of both cholesterol and B-Sit can cause lipid peroxidation. For these reasons, B-Sit should always be administered in a composition that includes complementary antioxidants, in order to counter the ROS activity and support its action in the cell membrane and intracellular environment. Regarding the effects on cancer, the practical effects of inadequate or incompatible antioxidants with B-Sit would be a leveling off at a balance between increased apoptosis and increased proliferation.