Читать книгу Transporters and Drug-Metabolizing Enzymes in Drug Toxicity - Albert P. Li - Страница 3

1 Chapter 2Table 2.1 Genetic diseases related to hepatic transporters.Table 2.2 Selected reports for the association between gene variations and dr...

2 Chapter 3Table 3.1 A summary of the key mechanisms of drug‐induced toxicity for the 12...

3 Chapter 5Table 5.1 Associations between polymorphisms affecting drug metabolism and DI...Table 5.2 Summary of selected NAT2 candidate gene studies concerned with ison...

4 Chapter 7Table 7.1 MS applications in detection of GSH trapped reactive metabolites.

5 Chapter 10Table 10.1 Major hepatic bile acid transporters and their bile salt substrate...Table 10.2 A non‐exhaustive list of non‐cholestatic and cholestatic drugs wit...

6 Chapter 11Table 11.1 Selected renal transporters on apical and basolateral membrane of ...Table 11.2 Relativein vitro inhibition on human OCT2, MATE1, and MATE2K by se...Table 11.3 Effects of selective renal transporter inhibition on metformin pha...Table 11.4 Effects of selective renal transporter inhibition on creatinine ch...Table 11.5 Examples of drug‐induced nephrotoxicity and biomarkers used to ass...

7 Chapter 12Table 12.1 ABC and SLC transporters in CNS fluid barriers.Table 12.2 Physicochemical and binding properties of selected anti‐histamines...Table 12.3 Selected opioids and drug transporter interactions at the BBB.

8 Chapter 13Table 13.1 Partial list of ototoxic drugs.

9 Chapter 15Table 15.1 In vitro enzyme/transporter inhibition constants and human drug exposu...Table 15.2 1/R‐assessment analysis following single or parallel worst‐case pa...