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1 1.3.1 List the problems with the first Salk trial.

2 1.3.2 How did the second Salk trial overcome the problems in the first Salk trial?

3 1.3.3 Why were the sample sizes so large for the Salk trials?

4 1.3.4 Find an example of another failed medical experiment. Be sure to articulate why it failed.

5 1.3.5 Plot the number of cases of polio in the United States by year; the data are in polio.csv . The eradication of polio is obvious as time increases. What is noticeable about the period before the introduction of the polio vaccine?