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Checking out other receptors

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CB1 and CB2 aren’t the only receptors in town. CBD has the incredible capability of interacting with more than 72 different receptors in the human body. Luckily, CBD’s promiscuity lends it to diverse applications, interactions, and functions. (Check out the preceding section for more on CBD’s interaction with CB1 and CB2).

Some of these other receptors and their functions are

 TRPV1 receptors: CBD binds to this transitory receptor known for temperature regulation. It’s also recognized for mediating pain response and perception.

 GABA-A receptor: GABA-A binds to neurons to decrease their activity; essentially, it calms them from overactivity that results in fear and anxiety. CBD is shown to change the shape of this receptor, increasing its calming effects on the brain. Preliminary research suggests it may go so far as to act as a sedative.

 Serotonin: Serotonin is a neurotransmitter that can directly affect your mood and emotions. When CBD interacts with TRPV1, it in turn can activate serotonin, reducing anxiety and boosting mood while mitigating pain response. Plainly speaking, CBD may relieve chronic anxiety.

 Mu opioid receptors: Mu receptors are one of many different types of opioid receptors on nerve cells. They primarily determine how strong of a pain-relieving effect an opioid has. CBD interacts with mu opioid receptors in a way that potentially amplifies the effects of opioids. In other words, CBD may enhance the pain-relieving properties of opioids like morphine.

 Dopamine: The dopamine molecule is a feel-good neurotransmitter. It plays a key role in human behavior, affecting goal-directed behavior and learning. CBD increases the quantity of dopamine in your body.

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