Читать книгу Neurology - Charles H. Clarke - Страница 71

The blood–brain barrier (BBB) is a concept – that divides the systemic compartment from the CNS and across which fluids, solutes and cells can pass selectively. This gives CNS machinery relative resistance to immune attack but it also provides an environment in which unique autoimmune processes can occur, that either limit or cause damage. The blood–nerve barrier (BNB) is less well understood – the endoneurial space of the peripheral nerve. The BNB is more permeable than the BBB, but it undoubtedly modifies immune responses that would occur if nerves were not shielded. See Chapter 10.