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2.3 SENSITIVITY AND SPECIFICITY

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Sensitivity and specificity are measures historically used in diagnostic situations but can be applied to other contexts as well. We can easily adapt the data in Table 2.1 to suit a brief discussion of these measures. We keep the same cell frequencies, but modify variable names so the data become a bit more applicable to a discussion of sensitivity and specificity (see Table 2.3).

The sensitivity of the diagnostic instrument is the probability that the test is positive given that the individual has the disease. In the margins, we see that 30 people have the disease, of which 20 were diagnosed with it. Thus, the sensitivity of the test is 20/30 = 0.66. The specificity of the diagnostic instrument is the probability that the test is negative, given that the individual does not have the disease. In the margins, we see that 20 people do not have the disease, of which 15 were diagnosed with not having the disease. Hence, the specificity of the test is 15/20 = 0.75. The overall prevalence of the disease is equal to 30/50 (i.e., 30 people have the disease out of 50). One can also compute what are known as positive and negative predictive values from such tables. For these and other measures useful for diagnostic situations, see Dawson and Trapp (2004).

Applied Univariate, Bivariate, and Multivariate Statistics

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