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The randomised trial of Weng, Li, Xu, et al. (2008) compared, in newly diagnosed patients with type 2 diabetes, three treatments: multiple daily insulin injections (MDI), continuous subcutaneous insulin infusion (CSII) and oral hypoglycaemic agent (OHA).

Key features include the following:

 Design: Nine centres, randomised three‐group comparison,

 Endpoint: Time of glycaemic remission,

 Size: 410 newly diagnosed patients with type 2 diabetes,

 Analysis: Cox proportional‐hazards regression model,

 Conclusion: Early intensive therapy has favourable outcomes on recovery and maintenance of β‐cell function and protracted glycaemic remission compared to OHA.