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1 Chapter 3Table 2 Operational mattress definitionsTable 4 Minimisation factors

2 AppendixTable T1 Random numbersTable T2 The Normal distribution function – Probability,γ, that a Normally ...Table T3 Percentage points of the standardised Normal distribution for givenα...Table T4 The value tabulated ist_{1 − α/2}, such that if X i...Table T5 Simon, Wittes and Ellenberg designTable T6 The multiplierκ of the estimated standard deviation, s_Pilot, to ob...Table T7 Total sample size for a two equal group Main trial for standardised dif...Table T8 Optimal values of Pilot, Main and hence Overall two equal‐group compara...