Читать книгу Horse Genetics - Ernest Bailey - Страница 55

A single nucleotide base change in the intronic splice site of the KIT gene causes an unusual transcript causing the sabino1 phenotype. For this variant, an entire exon is absent from the resulting protein. In this case the variant is a SNP that destroys the signal for creating the splice. However, since it is not in an exon, it is neither synonymous nor non-synonymous (Brooks and Bailey, 2005; Chapter 9).