Читать книгу Horse Genetics - Ernest Bailey - Страница 57

Mutation can alter splice sites for excision of introns or DNA sequences that serve as binding sites for regulatory molecules determining time and amount of expression. The variant affecting the gene for appaloosa (leopard spotting) is an insertion outside the coding portion of the gene that alters the amount of transcription by the TRPM1 gene (Bellone et al., 2010).