Читать книгу Clinical Pharmacology and Therapeutics - Группа авторов - Страница 108
Hyperthyroidism
ОглавлениеPropylthiouracil tends to be used more often than carbimazole during pregnancy. Propylthiouracil is less lipid‐soluble and more protein‐bound and crosses less well into the foetus and breast milk. The dose should be titrated against maternal thyroid function and adjusted to maintain free T4 in the upper non‐pregnant range. Requirements tend to decrease in pregnancy. Propranolol may be used to treat symptoms and there are no known teratogenic effects. Radioactive iodine should not be given to any women who is or may be pregnant.