Читать книгу Clinical Pharmacology and Therapeutics - Группа авторов - Страница 96

During this stage major body structures have been formed, and it is their subsequent development and function that can be affected:

1 Antithyroid drugs cross the placenta and can cause foetal and neonatal hypothyroidism

2 Tetracyclines inhibit bone growth and discolour teeth

3 Angiotensin‐converting enzyme inhibitors can seriously damage foetal kidney function

4 Warfarin can cause bleeding into the foetal brain

5 Drugs with dependence potential, e.g. benzodiazepines and opiates, which are taken regularly during pregnancy, can result in withdrawal symptoms in the neonate