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 Pulse contour cardiac output (PiCCO) requires the insertion of a central venous catheter and a thermodilution arterial line.

 It provides hemodynamic monitoring by combining pulse contour analysis and a transpulmonary thermodilution technique to provide a continuous display of PiCCO cardiac index (L/min/m2) and stroke volume (mL/kg).

 Calibration of the PiCCO to more accurate transpulmonary thermodilution cardiac output measurements needs to be repeated every 8 hours, or more frequently if the patient is hemodynamically unstable.

 Additional data derived from the PiCCO system include:Extravascular lung water index (mL/kg).Global end‐diastolic volume (measure of cardiac preload in mL/m2).Systemic vascular resistance index (dyn·s/cm5/m2).Stroke volume variation (%).