Читать книгу Protocols for High-Risk Pregnancies - Группа авторов - Страница 105
Cystic fibrosis Clinical significance
ОглавлениеCystic fibrosis is a progressive disease that has severe effects on the pulmonary, pancreatic, hepatic, and gastrointestinal systems. The majority of males with cystic fibrosis also have primary infertility due to absence of the bilateral vas deferens. The median predicted survival is 42 years of age. The incidence is 1 in 2500 among Caucasian individuals but significantly lower in other populations. The carrier rates are approximately 1 in 25 for Ashkenazi Jewish and Caucasian populations, 1 in 60 for Hispanics and African Americans, and 1 in 94 for those of Asian ancestry.