Читать книгу Poisonous Plants and Phytochemicals in Drug Discovery - Группа авторов - Страница 52

Phytotoxins have various mechanistic activities on the physiological processes of the organisms they are affecting. These include, but are not limited to, lipid biosynthesis (cyperine: Ascochyta cypericola), energy production (tentoxin: Alternaria spp.), the polymerization of actin (cytochalasins: many fungal species), and reactive oxygen species production (cercosporin: Cercospora spp.) [1]. Generally, their mechanism of action is to interact with body cells and possibly cause slow degeneration or other long‐lasting complications. Interventions against such adverse mechanisms involve blocking the mechanistic processes or introducing entirely new agents, such as known drugs, to undo or redirect the mechanisms.