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The echogenicity of the splenic parenchyma should be evaluated for diffuse and focal changes. Normal splenic parenchyma is homogeneous in appearance with fine echotexture, and its thin hyperechoic (bright white) capsule may be apparent on long‐axis (sagittal) views. Spleen parenchyma is generally mildly to moderately hyperechoic (brighter) to normal liver parenchyma (Figure 9.3A,B), and significantly hyperechoic (brighter) to normal renal cortex (Hecht 2008) (see Figure 9.3C,D).

Pearl: Remember the mnemonic “SLiCK” regarding relative normal echogenicity of spleen, liver and kidney cortex. Spleen (S) is hyperechoic (brighter) to liver (Li) which is slightly hyperechoic (brighter) or isoechoic (same shades of gray) to the cortex of the kidney (CK). For the feline, hepatic echogenicity is often compared to the adjacent falciform fat and the feline liver should be isoechoic to slightly hypoechoic to the falciform fat.

Figure 9.3. Echogenicity of spleen relative to liver and cortex of kidney. (A) Comparison of the echogenicity of spleen to the liver, unlabeled. (B) Same as (A) but labeled as liver (LIV) and spleen (SP). (C) Comparison of echogenicity of the spleen to the cortex of the left kidney, unlabeled. (D) Same as (C) but labeled as spleen (SP) and left kidney (LK).