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 Spleen size is subjective. A spleen that extends to a small or medium‐sized urinary bladder is considered enlarged.

 A folded spleen in a cat is always as a general rule considered abnormal and indicates splenomegaly (Hecht 2008).

 Normal cat spleen thickness is <10 mm (Reese et al. 2013).

 Benign nodular hyperplasia usually consists of nodules that are of homogeneous echotexture being either hypoechoic or hyperechoic.

 Single target lesions have a high predictive value for malignancy. When multiple target lesions are seen, the positive predictive value of malignancy increases from 74% to 81% (Cuccovillo and Lamb 2002).

 Normal echogenicity rule of thumb: the spleen (S) is more echogenic (hyperechoic) than the liver (Li) which is the same or slightly more echogenic (brighter) than the cortex of the kidney (CK), remembered as S > Li ≥ CK or by the mnemonic “SLiCK.” For the feline, hepatic echogenicity is often compared to the adjacent falciform fat and the feline liver should be isoechoic to slightly hypoechoic to the falciform fat.