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1.2 The Unique Fluorine Effects in Organic Reactions

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It is now gradually accepted that organofluorine reactions are usually distinct from regular organic reactions, and in many cases, fluorine substitution in an organic molecule imparts unique reactivity to the latter. As a result, direct application of the knowledge and experience acquired from regular organic reactions to organofluorine reactions often leads to failure or unexpected results. In this section, we provide some selected examples to highlight the unique features of organofluorine reactions. For more examples and discussions, one may refer to our recent tutorial review [4e].

Organofluorine Chemistry

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