Читать книгу The SAGE Encyclopedia of Stem Cell Research - Группа авторов - Страница 321

Tendinosis, or chronic tendon injury, results due to tendon damage at a cellular level. It is caused by micro-tears in the connective tissue, leading to an increase in tendon repair cells in and around the tendon. This reduces the tensile strength, thereby increasing the chance of tendon rupture. Characteristics of tendinosis include degenerative changes in the collagenous matrix, hypercellularity, hypervascularity, and a lack of inflammatory cells. Symptoms resemble tendinitis features, with the increased water content and disorganized collagen matrix detected by ultrasonography or magnetic resonance imaging (MRI).