Читать книгу The SAGE Encyclopedia of Stem Cell Research - Группа авторов - Страница 358

Based originally on the three documents described above, the seven main principles now in practice in all research on human subjects are that the clinical trials research must have each of the following:

 Social and clinical value

 Scientific validity

 Fair subject selection

 Favorable risk-benefit ratio

 Independent review

 Informed consent

 Respect for potential and enrolled subjects

An additional ethical requirement of clinical trials is collaborative partnership, meaning that the clinical research must involve the community in which it occurs. The community should participate in planning, conducting, and overseeing research, and in integrating the results of the research into the community health system. The way that this is achieved is through community advisory boards in which patient advocates participate, as well as advocates for research funding.

Astra I. Chang

University of California, Davis

See Also: Clinical Trials (Adult Cells), Ethics of; Clinical Trials Outside the United States.