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Introduction

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A cytologic examination of the uterus should always be performed in conjunction with a uterine culture. Cytologic evaluation of the uterus involves the collection and interpretation of cells lining the uterus (endometrium) and within the uterine lumen. Endometrial cytology is a rapid, inexpensive technique to detect the presence of endometritis in the mare.

There are circumstances whereby a uterine cytology may be normal (no inflammatory cells) and an infection is still present. These include isolated infections, deep‐seated infections, or infections early in their course. It is also more common to have a negative cytology (i.e., no inflammatory cells) in the presence of an Escherichia coli infection than in the presence of a Streptococcus equi subspecies zooepidemicus infection.

Typically a guarded swab or a brush is used to obtain a uterine cytology sample; collection of a uterine sample with unguarded swabs may result in significant contamination from the vestibule, vagina, and cervix. A low volume uterine lavage may be more diagnostic than swab or brush samples in situations where isolated infections are present (see Chapter 18).

Equine Reproductive Procedures

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