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Parenteral administration refers to the administration of drugs by a route other than the oral route. This would include intravascular, intramuscular, subcutaneous, intradermal, intra‐synovial, and epidural routes of administration. Intravascular and epidural injections will be discussed in subsequent chapters. Subcutaneous and intra‐dermal routes of administration have a low risk of complications and will not be reviewed in this chapter. This chapter will focus on complications of intramuscular and intra‐synovial injections.