Читать книгу Biological Mechanisms of Tooth Movement - Группа авторов - Страница 66

According to Lundy and Linden (2004) it is generally accepted that the nervous system contributes to the pathophysiology of peripheral inflammation, and a neurogenic component has been implicated in many inflammatory diseases including periodontitis. Neurogenic inflammation should be regarded as a protective mechanism, which forms the first line of defense and protects tissue integrity. Sensory neuropeptides play important roles in neurogenic inflammation, including vasodilatation, plasma extravasation, and recruitment of immune cells. However, a more extensive function for neuropeptides in the regulation of immune cell activity has also been proposed. During inflammation, there is a sprouting of peptidergic peripheral fibers and increased neuropeptide content.