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Immunohistochemical Studies and Molecular Features

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IHC staining for HSV (HSV 1 and 2 cocktail stain) may be useful for suspected infections if diagnostic inclusions are not readily identified on H&E sections. Similarly, IHC for CMV is useful to highlight infected cells without typical CMV morphology, and may be more sensitive than light microscopy.

PCR for M. tuberculosis may be useful in selected cases.


Figure 2.8 High‐magnification evaluation of Figure 2.7 demonstrated (a) endothelial CMV infection (b) confirmed by immunohistochemistry.

Gastrointestinal Pathology

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