Читать книгу Current Perspectives in Kidney Diseases - Группа авторов - Страница 36

The use of citrate represents a valid alternative to traditional anticoagulation with heparin during CRRT since it reduces the bleeding risk and increases the efficiency of the treatment. The increase of filter life span in fact, is not a goal to be pursued in itself, but the reduction of the filter clotting events within the first 48–72 h reduces the discrepancy between the prescribed and delivered dialysis doses. With recent technological innovations, the RCT during CRRT can be conducted safely with minimal risk of complications even in patients at the highest risk of citrate accumulation such as patients with liver dysfunction.