Читать книгу Graves' Orbitopathy - Группа авторов - Страница 13

GO can affect people of all races. Genetic susceptibility to Graves’ disease varies between races [17], and there is some evidence that amongst patients with Graves’ disease, susceptibility to GO also varies between races. For example, Europeans appear more likely to develop GO than Japanese Asians [18]. There are very few data on racial differences for both prevalence and presentation of GO, and the influence of important confounding factors such as smoking needs to be considered.

There is known to be significant variation in normal exophthalmometry values between races [19], with Chinese Asians showing significantly lower values than Caucasians [20], while Black people have relatively shallow orbits and show higher values. Hence exophthalmos should be assessed in relation to the normal range for the patient’s race and gender.