Читать книгу Graves' Orbitopathy - Группа авторов - Страница 18

Determining the phase of GO at each clinical assessment is fundamental to formulating an appropriate management plan. This is because immunomodulatory therapies can only be effective while there is active inflammation. On the other hand, certain surgical treatments, for example strabismus surgery, should only be undertaken when GO is inactive and there is no further chance of spontaneous change. Furthermore, sight-threatening disease occurs insidiously during active GO; therefore symptoms and signs of corneal ulceration and DON should be specifically sought during this phase [4].