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Preface to the Third, Revised and Expanded Edition
ОглавлениеIt is precisely 10 years ago that the first edition of Graves’ Orbitopathy: A Multidisciplinary Approach was published. The book has become rather popular, warranting a third edition. What has not changed is the successful question-and-answer format of the book. Also, although authors have changed, all are members of EUGOGO adhering to a multidisciplinary approach in the management of Graves’ orbitopathy (GO), preferably in combined thyroid-eye clinics. These EUGOGO principles have been widely adopted, and combined thyroid-eye clinics are now found all over Europe.
Much has happened in the field of GO in the last 10 years. Patients present now with less severe and less active disease than in the past. Presumably this is related to a secular decline in the prevalence of smoking, and to an earlier diagnosis and treatment of associated Graves’ hyperthyroidism. Novel immunosuppressive treatment modalities have become available. Patient-reported outcomes and the socioeconomic consequences of GO have been given more attention. Actually, we have obtained a better understanding of almost all aspects of GO, and that is duly reflected in the updated text. New chapters have been added on several topics, dealing with comorbidity (diabetes, osteoporosis, dry eye syndrome, glaucoma, cataract, retinopathy), local treatment modalities (artificial tears, prisms, botulinum toxin), novel immunosuppressive treatments (rituximab, teprotumumab, tocilizumab), protocols (selenium, glucocorticoids, retrobulbar irradiation, cyclosporine, rituximab), and questions frequently asked by patients (the patient’s view).
New centres have become EUGOGO members. EUGOGO remains active in performing clinical and basic research studies, and in organizing annual GO teaching courses with real-life investigation of patients. Formal ETA/EUGOGO guidelines on the management of GO were published in 2016. The third edition of this book reflects very well the continuous activity inside and outside the EUGOGO group on this peculiar thyroid eye disease, which is still one of the remaining enigmas in the field of autoimmune thyroid diseases.
On behalf of EUGOGO,
Wilmar M. Wiersinga, Editor
George J. Kahaly, Co-Editor
Amsterdam and Mainz, June 2017