Читать книгу Intracranial Gliomas Part II - Adjuvant Therapy - Группа авторов - Страница 55

Again there exists variability in the dose as well as the volume treated. Typically, the high-risk region is irradiated to a total dose of approximately 60 Gy in 1.8–2 Gy per fraction. At MD Anderson Cancer Center, IMRT with SIB technique is usually utilized. The GTV is defined as the resection cavity, residual enhancing disease, and T2 hyperintense non-enhancing disease; it is treated with appropriate setup margin to a dose of 57 Gy in 30 fractions. Lower risk region (typically defined as 1.5 cm margin beyond the aforementioned volume) is treated with an appropriate setup margin to a dose of 50 Gy in 30 fractions.