Читать книгу Parathyroid Disorders - Группа авторов - Страница 21

Renal stones are a major complication of PHPT. Generally, patients with PHPT who develop renal stones are younger and more often male [18]. Hypercalciuria likely contributes to an increased risk of renal stones. The pathogenesis of increased renal stone formation in PHPT has not yet been fully elucidated. Hypercalciuria by itself does not fully explain the increased risk, and only limited data are currently available on the potential impact of other biochemical abnormalities, such as renal acidification abnormalities on the risk of stones in PHPT [18].